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Management of patients presenting to the Emergency Department with symptoms  >4-28 days post the Astra Zeneca vaccine

The condition of concern is Covid-19 Vaccine induced Thrombosis and Thrombocytopenia (VITT)

Cases usually present with progressive thrombosis, with a high preponderance of cerebral venous sinus thrombosis. Splanchnic vein thrombosis is common and pulmonary embolism and arterial ischaemia are also seen. Bleeding can be significant and unexpected. Symptoms of concern are

  • Persistent or severe headaches, seizures or focal neurology, • Shortness of breath, persistent chest or abdominal pain, • Swelling, redness, pallor or cold lower limbs

ED pathway 20210410